• Users Online: 98
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
Year : 2021  |  Volume : 7  |  Issue : 2  |  Page : 125-131

Masquelet's induced membrane technique for reconstruction of large extra-articular intercalary bone defect

1 Department of Orthopedic Surgery, Ain Shams General Hospital, Cairo, Egypt
2 Department of Orthopedic Surgery, Zagazig University, Cairo, Egypt
3 Department of orthopaedic surgery Alzahraa University Hospital, Al-Azhar University, Cairo, Egypt
4 Department of Orthopedic Surgery, Al-Azhar University Hospitals, Cairo, Egypt
5 Department of orthopedic Surgery, Johns Hopkins Aramco Hospital, Dhahran, Kingdom of Saudi Arabia
6 Department of Orthopedic Surgery, University of Louisville, Louisville, KY, USA
7 Department of Orthopedic Surgery, Al-Azhar University Hospital, Asyut, Egypt
8 Department of Orthopedic, Texas Tech University, El Paso, TX, USA

Correspondence Address:
Dr. Yasser Elbatrawy
Department of Orthopedic Surgery, Faculty of Medicine for Girls, Alzahraa University Hospital, Al-Azhar University, Cairo
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jllr.jllr_30_21

Rights and Permissions

Background: Intercalary bone defects are challenging for both surgeon and patient. The Masquelet's induced membrane technique saves bone consolidation time is less technically demanding than other techniques and achieves good results in the reconstruction of large extra-articular intercalary bone defects. Patients and Methods: This prospective study reviewed 60 patients treated with the induced membrane technique. Patients with femoral or tibial extra-articular intercalary bone defects ≥5 cm long, occurring either posttraumatically or after debridement of infected bone, were included in the study. Patients with bone defects <5 cm long were excluded from the study. The male-to-female ratio was 17:3. Patient age ranged from 10 to 50 years. Recorded outcomes included union, infection, residual deformity, soft-tissue healing, persistent pain, return to previous occupation, permanent joint contracture, and patient satisfaction. Results: Mean follow-up was 3.1 years (range, 2.2–4 years). Mean intercalary bone defect measured 7.5 cm (range, 5–13 cm) in length. Forty-five of 60 patients had open fractures. Thirty-nine underwent Ilizarov fixation, 12 with locked plates, and nine with a limb reconstruction system. The mean interval between the first and second stages was 56 days (range, 42–84 days). Bony union was achieved in 51 patients (85%). Twelve patients experienced relapsed infection during treatment, three because of flap failure, and nine because of inadequate debridement. Three were treated with repeat debridement and free vascularized flap after gastrocnemius flap, six underwent bone transport, and three required amputation. Conclusion: The Masquelet's induced membrane technique was highly effective in achieving the union of large femoral intercalary bone defects, with mixed results in the tibia.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded34    
    Comments [Add]    

Recommend this journal